COVID vaccination wavefront

[Runtime Error]

Originally Posted by storm5510

I fear the timeline for this will be long. Then, there is the new variant. I wonder if the current vaccine is already obsolete? My next doctor's appointment is in early March. I will have to ask...

Obsolete is a strong word. The current vaccine will confer partial immunity against new mutations. How much depends on which mutations occur. Most mutations will not affect the proteins that the current vaccines target. Relatedly, even if you got a flu shot several years ago, it still provides some protection against this year's flu. (But that is not an excuse to skip this year's flu shot!)

[masser]

Originally Posted by storm5510

I fear the timeline for this will be long. Then, there is the new variant. I wonder if the current vaccine is already obsolete? My next doctor's appointment is in early March. I will have to ask...

You might want to check with local pharmacies to see if they can vaccinate you before early March. A relative of mine is 76 and I suspect they will be vaccinated in the next month.

[Dr Sardonicus]

Originally Posted by Runtime Error

<snip>
Relatedly, even if you got a flu shot several years ago, it still provides some protection against this year's flu. (But that is not an excuse to skip this year's flu shot!)

The current year's vaccine isn't always a good match to what turns out to be this season's strain, so I've kind of hoped that if I get the flu shot every year, I might have significant antibodies to different strains targeted by recent years' flu shots. That way, if this year's shot isn't a good match, some of the old buckshot still might hit.

[Batalov]

The learned immune system can recognize the fragments of a significantly similar virus. The spike protein fragments of 6-7 aminoacids in length are recognized by immune cells. In new Covid-19 variants, there are only 1 or 2 changes in the spike proteins (S1, S2) length (out of several hundred).
There are experiments ongoing to ascertain that theory, at Walter Reed, at BioNTec and more.

There is a good open-text article: https://www.nature.com/articles/s41392-020-00352-y
They argue that some folks that had had old SARS may have immune system that would recognize Covid-19 even though those are much more different than the several known new variations of the 2019 Covid-19 strain.

What is relatively good about coronaviruses as a a class: they mutate much slower than e.g. flu. The vaccine next year might be a cocktail of two (or whatever is practical), but this year there is no reason to delay vaccinations with these two good looking vaccines (AZ/Oxford is also nearly there).

[pinhodecarlos]

Maybe still early stages but I was looking for figures regarding patients with Parkinson Disease who already took the vaccine, what was the outcome reaction if any or none.

[CRGreathouse]

Originally Posted by pinhodecarlos

Maybe still early stages but I was looking for figures regarding patients with Parkinson Disease who already took the vaccine, what was the outcome reaction if any or none.

I couldn't find anything on LitCovid or the BNT162b2 trial paper (NEJM).

[pinhodecarlos]

Covid-19: Oxford-AstraZeneca coronavirus vaccine approved for use in UK.
https://www.bbc.co.uk/news/health-55280671

[pinhodecarlos]

On the link below you can follow the covid-19 vaccination administer so far worldwide.

https://ourworldindata.org/covid-vaccinations

[paulunderwood]

The ck ups have begun. Despite the tested and recommended dose interval of three weeks by the manufacturer between jabs, the uk tory government playing pseufo-scientists know better and have said that 12 weeks is good.

https://www.theguardian.com/society/...f-second-doses

[PhilF]

Originally Posted by paulunderwood

The ck ups have begun. Despite the tested and recommended dose interval of three weeks by the manufacturer between jabs, the uk tory government playing pseufo-scientists know better and have said that 12 weeks is good.

https://www.theguardian.com/society/...f-second-doses

Hmmm. I thought only Trump was smarter than the scientists.

[a1call]

Originally Posted by pinhodecarlos

On the link below you can follow the covid-19 vaccination administer so far worldwide.

https://ourworldindata.org/covid-vaccinations

It is fascinating that Israel has vaccinated (1st dose to be exact) close to 10% of its population already while other countries who generally consider themselves super-powers or otherwise on top of the scientific/military/... Pyramid lag so far behind.

Pride is such a set-backer.