Well, currently "George's dream build" consists of a bunch of Radeon VII GPUs - 10x the performance (of a modern quadcore), 3x the power consumption and 3x the cost. Unfortunately, they are out of production, and so you need to look for used ones.
The new Zen 3 parts with 64MB L3 should be good value for GIMPS.
I am also cautiously optimistic about the potential of RX 6000 series GPUs with the 128 MB "infinity cache".
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