Prime95 25.11
 

Times for PRP test of 59912*5^325037+1 on my 2.66GHz Core 2 Duo (1 core):

mprime 25.9: ~51 minutes
mprime 25.11: ~18 minutes

Almost 3 times faster!

These very radical speed increases are the result of v25.11 of the gwnum math library (used by Prime95, PRP, LLR, and PFGW) being optimized for non-power-of-2 numbers. (Previously it was only optimized for base 2.) At this time, both Prime95/mprime and PFGW have been updated to take advantage of this, though at the moment PFGW still suffers from a minor issue where the first character of its residuals is incorrect (thus it wouldn't work for SR5, since it would be flagged as incorrect during doublechecking).

Thus, for now, Prime95 would probably be the best way to go for SR5 members wishing to utilize one of the new, faster programs for manual testing. PFGW should be fixed soon to remedy the residue bug, and I expect LLR will be updated as well to utilize the new math library.